Drug interactions
Terazosin + Treprostinil
Severity: Moderate
Terazosin and Treprostinil: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Treprostinil is a strong vasodilator and may add to the blood pressure lowering of terazosin, causing symptomatic hypotension or syncope.
What this interaction means in plain words
Terazosin and Treprostinil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Terazosin belongs to Genitourinary; Treprostinil belongs to Cardiovascular.
Why it happens
Additive vasodilation through prostacyclin-receptor agonism and alpha-1 blockade.
What to do
Monitor blood pressure when starting or adjusting either drug and reduce the antihypertensive dose if hypotension develops.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Terazosin
- Alfuzosin + Terazosin Major
- Amifostine + Terazosin Major
- Avanafil + Terazosin Major
- Doxazosin + Terazosin Major
- Dutasteride-tamsulosin + Terazosin Major
- Lofexidine + Terazosin Major
Other interactions of Treprostinil
Frequently asked questions
Can I take Terazosin with Treprostinil?
MediHelp rates the interaction as moderate. Terazosin and Treprostinil can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Treprostinil is a strong vasodilator and may add to the blood pressure lowering of terazosin, causing symptomatic hypotension or syncope.
How serious is the interaction between Terazosin and Treprostinil?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood pressure when starting or adjusting either drug and reduce the antihypertensive dose if hypotension develops.
What other medicines interact with Terazosin?
MediHelp also lists interactions of Terazosin with, for example, Alfuzosin, Amifostine, Avanafil. The full list is on the Terazosin page.
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