Drug interactions
Tetrabenazine + Triptorelin
Severity: Moderate
Tetrabenazine and Triptorelin: moderate interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Tetrabenazine causes a small but definite QT prolongation, and triptorelin may add to this through androgen deprivation. The combination may increase the risk of torsades de pointes.
What this interaction means in plain words
Tetrabenazine and Triptorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Tetrabenazine belongs to Central Nervous System; Triptorelin belongs to Endocrine.
Why it happens
Additive QT prolongation.
What to do
Obtain a baseline ECG and correct electrolyte abnormalities. Repeat ECG after dose changes and avoid use in patients with congenital long QT.
What to ask your pharmacist
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Other interactions of Triptorelin
Other interactions of Tetrabenazine
- Dronedarone + Tetrabenazine Contraindicated
- Isocarboxazid + Tetrabenazine Contraindicated
- Linezolid + Tetrabenazine Contraindicated
- Phenelzine + Tetrabenazine Contraindicated
- Pimozide + Tetrabenazine Contraindicated
- Procarbazine + Tetrabenazine Contraindicated
Frequently asked questions
Can I take Tetrabenazine with Triptorelin?
MediHelp rates the interaction as moderate. Tetrabenazine and Triptorelin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Tetrabenazine causes a small but definite QT prolongation, and triptorelin may add to this through androgen deprivation. The combination may increase the risk of torsades de pointes.
How serious is the interaction between Tetrabenazine and Triptorelin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Obtain a baseline ECG and correct electrolyte abnormalities. Repeat ECG after dose changes and avoid use in patients with congenital long QT.
What other medicines interact with Triptorelin?
MediHelp also lists interactions of Triptorelin with, for example, Amisulpride, Arsenic trioxide, Bedaquiline. The full list is on the Triptorelin page.
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