Drug interactions
Tiludronate + Voclosporin
Severity: Minor
Tiludronate and Voclosporin: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Voclosporin can reduce renal function and tiludronate is eliminated by the kidney, so exposure to tiludronate may rise if kidney function declines. The practical risk is small with oral bisphosphonate use.
What this interaction means in plain words
Tiludronate and Voclosporin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Tiludronate belongs to Musculoskeletal; Voclosporin belongs to Miscellaneous.
Why it happens
Voclosporin-related reduction in glomerular filtration may reduce renal clearance of tiludronate; largely theoretical.
What to do
Monitor serum creatinine and eGFR periodically. Reassess tiludronate use if renal function declines markedly.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
Pro+ members
Unlock the full page
Create an account and start a Pro+ trial to unlock the full management advice for Tiludronate and Voclosporin, the additional notes, the evidence detail and the whole-prescription interaction checker.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Try Pro+ free for 14 days on the web. No card needed.
Other interactions of Tiludronate
- Acetylsalicylic acid + Tiludronate Moderate
- Aluminum hydroxide + Tiludronate Moderate
- Calcium acetate + Tiludronate Moderate
- Calcium carbonate + Tiludronate Moderate
- Calcium chloride + Tiludronate Moderate
- Calcium citrate + Tiludronate Moderate
Other interactions of Voclosporin
- Clarithromycin + Voclosporin Contraindicated
- Cyclosporin + Voclosporin Contraindicated
- Ensitrelvir + Voclosporin Contraindicated
- Itraconazole + Voclosporin Contraindicated
- Ketoconazole + Voclosporin Contraindicated
- Posaconazole + Voclosporin Contraindicated
Frequently asked questions
Can I take Tiludronate with Voclosporin?
MediHelp rates the interaction as minor. Tiludronate and Voclosporin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Voclosporin can reduce renal function and tiludronate is eliminated by the kidney, so exposure to tiludronate may rise if kidney function declines. The practical risk is small with oral bisphosphonate use.
How serious is the interaction between Tiludronate and Voclosporin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and eGFR periodically. Reassess tiludronate use if renal function declines markedly.
What other medicines interact with Tiludronate?
MediHelp also lists interactions of Tiludronate with, for example, Acetylsalicylic acid, Aluminum hydroxide, Calcium acetate. The full list is on the Tiludronate page.
Full monographs, dosing and an interaction checker in the MediHelp app
Open the complete reference, check multi-drug interactions and use dosing tools in the MediHelp app.
