Drug interactions
Ublituximab + Valacyclovir
Severity: Minor
Ublituximab and Valacyclovir: minor interaction.
Last updated
For healthcare professionals — reference only. This page is a brief summary, not medical advice and not a substitute for official labeling or clinical judgement. Always verify before prescribing or dispensing.
Summary
Ublituximab depletes B cells and raises the risk of infections, including herpesvirus reactivation. Valacyclovir does not lose potency, but patients remain susceptible to infection despite antiviral therapy.
What this interaction means in plain words
Ublituximab and Valacyclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Ublituximab belongs to Miscellaneous; Valacyclovir belongs to Anti Virals.
Why it happens
Immunosuppression from B-cell depletion by ublituximab; no direct pharmacokinetic interaction.
What to do
Continue valacyclovir when indicated and monitor for herpes infections. Do not assume antiviral therapy fully protects against infection.
What to ask your pharmacist
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Other interactions of Valacyclovir
- Talimogene laherparepvec + Valacyclovir Major
- Bacitracin + Valacyclovir Moderate
- Cilastatin-imipenem + Valacyclovir Moderate
- Elvitegravir / cobicistat / emtricitabine / tenofovir df + Valacyclovir Moderate
- Imipenem / cilastatin / relebactam + Valacyclovir Moderate
- Imipenem / cilastatin + Valacyclovir Moderate
Other interactions of Ublituximab
Frequently asked questions
Can I take Ublituximab with Valacyclovir?
MediHelp rates the interaction as minor. Ublituximab and Valacyclovir have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Ublituximab depletes B cells and raises the risk of infections, including herpesvirus reactivation. Valacyclovir does not lose potency, but patients remain susceptible to infection despite antiviral therapy.
How serious is the interaction between Ublituximab and Valacyclovir?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Continue valacyclovir when indicated and monitor for herpes infections. Do not assume antiviral therapy fully protects against infection.
What other medicines interact with Valacyclovir?
MediHelp also lists interactions of Valacyclovir with, for example, Talimogene laherparepvec, Bacitracin, Cilastatin-imipenem. The full list is on the Valacyclovir page.
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