تداخل‌های دارویی
Atazanavir + Eletriptan
شدت: منع مصرف
Atazanavir and Eletriptan: contraindicated interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Atazanavir is a strong CYP3A4 inhibitor and markedly raises eletriptan exposure, increasing the risk of vasoconstrictive and other triptan adverse effects. Eletriptan labeling contraindicates use within 72 hours of potent CYP3A4 inhibitors, including HIV protease inhibitors.
معنای این تداخل به زبان ساده
Atazanavir and Eletriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Atazanavir belongs to Anti Virals; Eletriptan belongs to Central Nervous System.
چرا رخ می‌دهد
Strong inhibition of CYP3A4-mediated first-pass and systemic metabolism of eletriptan.
اقدام لازم
Do not give eletriptan within at least 72 hours of atazanavir. Use a triptan not metabolized by CYP3A4, such as rizatriptan or sumatriptan, with attention to its own precautions.
از داروساز چه بپرسید
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Atazanavir و Eletriptan، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Eletriptan
- Almotriptan + Eletriptan منع مصرف
- Ceritinib + Eletriptan منع مصرف
- Clarithromycin + Eletriptan منع مصرف
- Cobicistat + Eletriptan منع مصرف
- Conivaptan + Eletriptan منع مصرف
- Darunavir + Eletriptan منع مصرف
تداخلات دیگر Atazanavir
- Alfuzosin + Atazanavir منع مصرف
- Atazanavir + Avanafil منع مصرف
- Atazanavir + Dronedarone منع مصرف
- Atazanavir + Eplerenone منع مصرف
- Atazanavir + Ergotamine منع مصرف
- Atazanavir + Flibanserin منع مصرف
پرسش‌های متداول
Can I take Atazanavir with Eletriptan?
MediHelp rates the interaction as contraindicated. Atazanavir and Eletriptan are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Atazanavir is a strong CYP3A4 inhibitor and markedly raises eletriptan exposure, increasing the risk of vasoconstrictive and other triptan adverse effects. Eletriptan labeling contraindicates use within 72 hours of potent CYP3A4 inhibitors, including HIV protease inhibitors.
How serious is the interaction between Atazanavir and Eletriptan?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give eletriptan within at least 72 hours of atazanavir. Use a triptan not metabolized by CYP3A4, such as rizatriptan or sumatriptan, with attention to its own precautions.
What other medicines interact with Eletriptan?
MediHelp also lists interactions of Eletriptan with, for example, Almotriptan, Ceritinib, Clarithromycin. The full list is on the Eletriptan page.
تک‌نگاری کامل، دوزاژ و بررسی تداخل دارویی در برنامه MediHelp
مرجع کامل را باز کنید، تداخل چند دارو را بررسی کنید و از ابزارهای دوز در برنامه MediHelp استفاده کنید.
