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تداخل‌های دارویی

Cefaclor + Warfarin

شدت: متوسط

Cefaclor and Warfarin: moderate interaction.

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خلاصه

Cefaclor has been associated with raised INR and bleeding in patients taking warfarin, based mostly on case reports. The magnitude varies between patients, and acute infection may contribute.

معنای این تداخل به زبان ساده

Cefaclor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cefaclor belongs to Anti Bacterial; Warfarin belongs to Cardiovascular.

سطح شواهد: Low

چرا رخ می‌دهد

Not firmly established; possibly reduced gut-derived vitamin K or other effects on warfarin response.

اقدام لازم

Check INR within a few days of starting cefaclor and again after stopping it. Adjust the warfarin dose according to INR and watch for bleeding.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cefaclor و Warfarin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Cefaclor with Warfarin?

MediHelp rates the interaction as moderate. Cefaclor and Warfarin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Cefaclor has been associated with raised INR and bleeding in patients taking warfarin, based mostly on case reports. The magnitude varies between patients, and acute infection may contribute.

How serious is the interaction between Cefaclor and Warfarin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check INR within a few days of starting cefaclor and again after stopping it. Adjust the warfarin dose according to INR and watch for bleeding.

What other medicines interact with Cefaclor?

MediHelp also lists interactions of Cefaclor with, for example, Bcg vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefaclor page.

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