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Ceftazidime + Streptomycin

شدت: متوسط

Ceftazidime and Streptomycin: moderate interaction.

آخرین به‌روزرسانی

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خلاصه

Combining a cephalosporin with an aminoglycoside may raise the risk of kidney injury, and streptomycin carries its own risk of vestibular and hearing damage. The additive risk with ceftazidime is modest and mainly relevant in patients with renal impairment, older age or dehydration.

معنای این تداخل به زبان ساده

Ceftazidime and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Ceftazidime belongs to Anti Bacterial; Streptomycin belongs to Anti Bacterial.

سطح شواهد: Low

چرا رخ می‌دهد

Possible additive nephrotoxicity, with reduced renal clearance potentially increasing aminoglycoside exposure and ototoxicity.

اقدام لازم

Monitor serum creatinine and urine output, keep the patient hydrated, and adjust streptomycin dosing to renal function. Assess hearing and vestibular function in prolonged courses.

از داروساز چه بپرسید

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Ceftazidime و Streptomycin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Ceftazidime with Streptomycin?

MediHelp rates the interaction as moderate. Ceftazidime and Streptomycin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Combining a cephalosporin with an aminoglycoside may raise the risk of kidney injury, and streptomycin carries its own risk of vestibular and hearing damage. The additive risk with ceftazidime is modest and mainly relevant in patients with renal impairment, older age or dehydration.

How serious is the interaction between Ceftazidime and Streptomycin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine and urine output, keep the patient hydrated, and adjust streptomycin dosing to renal function. Assess hearing and vestibular function in prolonged courses.

What other medicines interact with Ceftazidime?

MediHelp also lists interactions of Ceftazidime with, for example, Amikacin, Cholera vaccine, Dexamethasone-tobramycin. The full list is on the Ceftazidime page.

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