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Cephaloridine + Furosemide

شدت: شدید

Cephaloridine and Furosemide: major interaction.

آخرین به‌روزرسانی

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خلاصه

Cephaloridine is a markedly nephrotoxic cephalosporin that is no longer in general use, and loop diuretics were reported to increase its renal toxicity. The combination could cause acute tubular injury, particularly with volume depletion.

معنای این تداخل به زبان ساده

Cephaloridine and Furosemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

سطح شواهد: Low

چرا رخ می‌دهد

Additive proximal tubular toxicity, with diuretic-induced volume depletion increasing renal cephaloridine accumulation.

اقدام لازم

Avoid the combination and choose a less nephrotoxic antibiotic. If it cannot be avoided, monitor renal function closely and maintain hydration.

از داروساز چه بپرسید

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cephaloridine و Furosemide، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Cephaloridine with Furosemide?

MediHelp rates the interaction as major. Cephaloridine and Furosemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cephaloridine is a markedly nephrotoxic cephalosporin that is no longer in general use, and loop diuretics were reported to increase its renal toxicity. The combination could cause acute tubular injury, particularly with volume depletion.

How serious is the interaction between Cephaloridine and Furosemide?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination and choose a less nephrotoxic antibiotic. If it cannot be avoided, monitor renal function closely and maintain hydration.

What other medicines interact with Furosemide?

MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.

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