تداخل‌های دارویی
Cisplatin + Furosemide
شدت: شدید
Cisplatin and Furosemide: major interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Both drugs can damage the cochlea, and loop diuretics given with cisplatin increase the risk of hearing loss and tinnitus, which may be permanent. Furosemide can also worsen cisplatin-related nephrotoxicity through volume depletion and electrolyte loss.
معنای این تداخل به زبان ساده
Cisplatin and Furosemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Cisplatin belongs to Oncology; Furosemide belongs to Cardiovascular.
چرا رخ می‌دهد
Additive ototoxicity affecting cochlear hair cells and the stria vascularis, plus additive renal and electrolyte effects.
اقدام لازم
Avoid routine concurrent use where possible and use furosemide only when needed for hydration-related volume overload. Obtain audiometry and monitor renal function, magnesium and potassium.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Cisplatin و Furosemide، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Furosemide
تداخلات دیگر Cisplatin
پرسش‌های متداول
Can I take Cisplatin with Furosemide?
MediHelp rates the interaction as major. Cisplatin and Furosemide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can damage the cochlea, and loop diuretics given with cisplatin increase the risk of hearing loss and tinnitus, which may be permanent. Furosemide can also worsen cisplatin-related nephrotoxicity through volume depletion and electrolyte loss.
How serious is the interaction between Cisplatin and Furosemide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine concurrent use where possible and use furosemide only when needed for hydration-related volume overload. Obtain audiometry and monitor renal function, magnesium and potassium.
What other medicines interact with Furosemide?
MediHelp also lists interactions of Furosemide with, for example, Amifostine, Amikacin, Carbenoxolone. The full list is on the Furosemide page.
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