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تداخل‌های دارویی

Citalopram + Cocaine

شدت: شدید

Citalopram and Cocaine: major interaction.

آخرین به‌روزرسانی

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محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

Cocaine blocks reuptake of serotonin, norepinephrine and dopamine, so combining it with an SSRI may increase serotonergic toxicity. Cocaine also has sympathomimetic and arrhythmogenic effects that may add to cardiac risk.

معنای این تداخل به زبان ساده

Citalopram and Cocaine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Citalopram belongs to Central Nervous System; Cocaine belongs to Central Nervous System.

سطح شواهد: Low

چرا رخ می‌دهد

Additive serotonergic effects from monoamine reuptake inhibition, with added sympathomimetic and QT-related cardiac effects.

اقدام لازم

Avoid concurrent use and counsel patients accordingly. Watch for features of serotonin toxicity and cardiovascular instability if exposure occurs.

از داروساز چه بپرسید

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Citalopram و Cocaine، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Citalopram with Cocaine?

MediHelp rates the interaction as major. Citalopram and Cocaine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Cocaine blocks reuptake of serotonin, norepinephrine and dopamine, so combining it with an SSRI may increase serotonergic toxicity. Cocaine also has sympathomimetic and arrhythmogenic effects that may add to cardiac risk.

How serious is the interaction between Citalopram and Cocaine?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid concurrent use and counsel patients accordingly. Watch for features of serotonin toxicity and cardiovascular instability if exposure occurs.

What other medicines interact with Citalopram?

MediHelp also lists interactions of Citalopram with, for example, Cisapride, Dronedarone, Escitalopram. The full list is on the Citalopram page.

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