تداخل‌های دارویی
Desogestrel-ethinyl estradiol + Griseofulvin
شدت: شدید
Desogestrel-ethinyl estradiol and Griseofulvin: major interaction.
آخرین به‌روزرسانی منابع: US FDA label
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Griseofulvin has been associated with breakthrough bleeding, menstrual irregularities and reduced reliability of combined hormonal contraceptives. This may result in unintended pregnancy. Griseofulvin is also teratogenic, which heightens the importance of reliable contraception.
معنای این تداخل به زبان ساده
Desogestrel-ethinyl estradiol and Griseofulvin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Desogestrel-ethinyl estradiol belongs to Endocrine; Griseofulvin belongs to Anti Fungals.
چرا رخ می‌دهد
Griseofulvin is thought to induce hepatic enzymes, including CYP3A4, increasing metabolism of contraceptive steroids.
اقدام لازم
Use a reliable non-hormonal contraceptive method alongside or instead of the pill during griseofulvin treatment and for about a month afterward. Counsel the patient on breakthrough bleeding as a warning sign.
از داروساز چه بپرسید
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Desogestrel-ethinyl estradiol و Griseofulvin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۷ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
منابع
تداخلات دیگر Desogestrel-ethinyl estradiol
تداخلات دیگر Griseofulvin
پرسش‌های متداول
Can I take Desogestrel-ethinyl estradiol with Griseofulvin?
MediHelp rates the interaction as major. Desogestrel-ethinyl estradiol and Griseofulvin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Griseofulvin has been associated with breakthrough bleeding, menstrual irregularities and reduced reliability of combined hormonal contraceptives. This may result in unintended pregnancy. Griseofulvin is also teratogenic, which heightens the importance of reliable contraception.
How serious is the interaction between Desogestrel-ethinyl estradiol and Griseofulvin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Use a reliable non-hormonal contraceptive method alongside or instead of the pill during griseofulvin treatment and for about a month afterward. Counsel the patient on breakthrough bleeding as a warning sign.
What other medicines interact with Desogestrel-ethinyl estradiol?
MediHelp also lists interactions of Desogestrel-ethinyl estradiol with, for example, Fezolinetant, Aminocaproic acid, Amobarbital. The full list is on the Desogestrel-ethinyl estradiol page.
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