تداخل‌های دارویی
Diphenoxylate-atropine + Revefenacin
شدت: متوسط
Diphenoxylate-atropine and Revefenacin: moderate interaction.
آخرین به‌روزرسانی
ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.
محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.
خلاصه
Revefenacin is an inhaled long-acting antimuscarinic with low systemic exposure, and atropine adds systemic anticholinergic activity. The combination may increase dry mouth, urinary retention, constipation and other anticholinergic effects.
معنای این تداخل به زبان ساده
Diphenoxylate-atropine and Revefenacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Diphenoxylate-atropine belongs to Gastrointestinal Tract; Revefenacin belongs to Respiratory.
چرا رخ می‌دهد
Additive antimuscarinic effects.
اقدام لازم
Monitor for anticholinergic effects such as urinary retention, constipation and dry mouth. Limit the duration of diphenoxylate-atropine.
از داروساز چه بپرسید
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
ویژه اعضای Pro+
باز کردن کل صفحه
یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Diphenoxylate-atropine و Revefenacin، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.
تداخلات دیگر Diphenoxylate-atropine
تداخلات دیگر Revefenacin
پرسش‌های متداول
Can I take Diphenoxylate-atropine with Revefenacin?
MediHelp rates the interaction as moderate. Diphenoxylate-atropine and Revefenacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Revefenacin is an inhaled long-acting antimuscarinic with low systemic exposure, and atropine adds systemic anticholinergic activity. The combination may increase dry mouth, urinary retention, constipation and other anticholinergic effects.
How serious is the interaction between Diphenoxylate-atropine and Revefenacin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic effects such as urinary retention, constipation and dry mouth. Limit the duration of diphenoxylate-atropine.
What other medicines interact with Diphenoxylate-atropine?
MediHelp also lists interactions of Diphenoxylate-atropine with, for example, Isocarboxazid, Phenelzine, Tranylcypromine. The full list is on the Diphenoxylate-atropine page.
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