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تداخل‌های دارویی

Influenza virus vaccine quadrivalent intranasal + Leflunomide

شدت: منع مصرف

Influenza virus vaccine quadrivalent intranasal and Leflunomide: contraindicated interaction.

آخرین به‌روزرسانی

ویژه کادر درمان — فقط جهت مرجع. این صفحه خلاصه‌ای کوتاه است، توصیه پزشکی نیست و جایگزین بروشور رسمی یا قضاوت بالینی نمی‌شود. پیش از تجویز یا تحویل دارو همیشه بررسی کنید.

محتوای بالینی این صفحه فقط به زبان انگلیسی موجود است.

خلاصه

The intranasal influenza vaccine contains live attenuated virus, which may replicate more readily in a patient immunosuppressed by leflunomide. This could cause vaccine-strain infection and the response may be reduced.

معنای این تداخل به زبان ساده

Influenza virus vaccine quadrivalent intranasal and Leflunomide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

سطح شواهد: Moderate

چرا رخ می‌دهد

Impaired lymphocyte function reduces control of live attenuated virus replication.

اقدام لازم

Avoid the live intranasal vaccine; use an inactivated injectable influenza vaccine instead.

از داروساز چه بپرسید

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

ویژه اعضای Pro+

باز کردن کل صفحه

یک حساب بسازید و دوره آزمایشی Pro+ را شروع کنید تا توصیه‌های کامل مدیریت Influenza virus vaccine quadrivalent intranasal و Leflunomide، یادداشت‌های تکمیلی، جزئیات شواهد و بررسی‌کننده تداخل برای کل نسخه را باز کنید.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Pro+ را ۱۴ روز رایگان در وب امتحان کنید. بدون نیاز به کارت.

پرسش‌های متداول

Can I take Influenza virus vaccine quadrivalent intranasal with Leflunomide?

MediHelp rates the interaction as contraindicated. Influenza virus vaccine quadrivalent intranasal and Leflunomide are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which may replicate more readily in a patient immunosuppressed by leflunomide. This could cause vaccine-strain infection and the response may be reduced.

How serious is the interaction between Influenza virus vaccine quadrivalent intranasal and Leflunomide?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live intranasal vaccine; use an inactivated injectable influenza vaccine instead.

What other medicines interact with Leflunomide?

MediHelp also lists interactions of Leflunomide with, for example, Bcg vaccine live, Measles mumps and rubella vaccine live, Measles mumps rubella and varicella vaccine live. The full list is on the Leflunomide page.

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