Référentiel des médicaments
Rocuronium
Rocuronium is a medicine in the class musculoskeletal. It is used for tracheal intubation.
- Classe médicamenteuse: Musculoskeletal
- Indications: tracheal intubation
Dernière mise à jour
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Le contenu clinique de cette page n'est disponible qu'en anglais.
L'essentiel
- Classe médicamenteuse
- Musculoskeletal
- Formes courantes
- injection, perfusion
- Dosages courants
- 50 mg/5 ml, 10 mg/ml, 10 mg
- Interactions connues
- 128 (Majeure: 13 · Modérée: 60 · Mineure: 55)
- Noms commerciaux
- 12
- Pays et marchés
- 4
Indications
Mécanisme d'action
Nondepolarizing skeletal muscle relaxant; cholinergic receptor antagonist; inhibits depolarization
Posologie adulte habituelle (résumé de la notice)
0.45-0.6 mg/kg IV, Maintenance: 0.1-0.2 mg/kg IV repeat PRN
Grossesse et allaitement
- Grossesse
- Safe Not teratogenic in rats or rabbits; late embryo loss at high doses was put down to lack of ventilation. Widely used for general anaesthesia, including caesarean section. US label: not recommended for rapid sequence induction in caesarean section. Use when needed for anaesthesia.
- Allaitement
- Safe Short acting, highly polar and poorly absorbed by mouth, so little reaches milk or the infant; LactMed: no infant effects reported. Breastfeed once the mother has recovered; with several anaesthetic drugs, follow the most restrictive one.
Effets indésirables signalés
- Transient hypotension
- Hypertension
- Apnea
- Dose-related tachycardia
Précautions particulières
- Neuromuscular transmission should be monitored continuously during administration and recovery with the help of a nerve stimulator
- Use caution in patients with significant hepatic disease; if used for rapid sequence induction in patients with ascites
Informez votre pharmacien ou votre médecin en cas de grossesse ou d'allaitement, de maladie rénale ou hépatique, d'allergies, ainsi que de tout autre médicament ou complément que vous prenez.
Principales interactions (128)
- Amikacin + Rocuronium Major
- Bacitracin-neomycin-polymyxin + Rocuronium Major
- Capreomycin + Rocuronium Major
- Clindamycin + Rocuronium Major
- Colistin + Rocuronium Major
- Dexamethasone-tobramycin + Rocuronium Major
- Gentamicin + Rocuronium Major
- Lincomycin + Rocuronium Major
- Magnesium + Rocuronium Major
- Polymyxin b + Rocuronium Major
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- Dosing by age, kidney and liver function, and further dose lines
- Paediatric dosing
- Patient counselling points
- Food interactions
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Questions fréquentes
What is Rocuronium used for?
Rocuronium is a medicine in the class musculoskeletal. It is used for Tracheal intubation.
What side effects have been reported with Rocuronium?
Transient hypotension, Hypertension, Apnea, Dose-related tachycardia.
Can Rocuronium be taken in pregnancy or while breastfeeding?
Pregnancy: Safe. Not teratogenic in rats or rabbits; late embryo loss at high doses was put down to lack of ventilation. Widely used for general anaesthesia, including caesarean section. US label: not recommended for rapid sequence induction in caesarean section. Use when needed for anaesthesia. Breastfeeding: Safe. Short acting, highly polar and poorly absorbed by mouth, so little reaches milk or the infant; LactMed: no infant effects reported. Breastfeed once the mother has recovered; with several anaesthetic drugs, follow the most restrictive one.
What does Rocuronium interact with?
MediHelp lists 128 known interactions for Rocuronium. Major: 13 · Moderate: 60 · Minor: 55. The most serious include Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin.
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