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Interactions médicamenteuses

Lincomycin + Rocuronium

Gravité: Majeure

Lincomycin and Rocuronium: major interaction.

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Résumé

Lincomycin has neuromuscular blocking activity and can potentiate rocuronium, prolonging paralysis and delaying return of spontaneous ventilation.

Ce que signifie cette interaction, en termes simples

Lincomycin and Rocuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.

Lincomycin belongs to Anti Bacterial; Rocuronium belongs to Musculoskeletal.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive neuromuscular blockade via presynaptic and postsynaptic inhibition of transmission by lincomycin.

Conduite à tenir

Monitor train-of-four and titrate rocuronium cautiously. Keep ventilatory support available until full recovery.

Questions à poser à votre pharmacien

  • Does the benefit of taking both outweigh the risk in my case?
  • Do I need any blood test, ECG or other check while on both?
  • What early warning signs should I watch for, and what should I do if they appear?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Lincomycin with Rocuronium?

MediHelp rates the interaction as major. Lincomycin and Rocuronium can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Lincomycin has neuromuscular blocking activity and can potentiate rocuronium, prolonging paralysis and delaying return of spontaneous ventilation.

How serious is the interaction between Lincomycin and Rocuronium?

MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor train-of-four and titrate rocuronium cautiously. Keep ventilatory support available until full recovery.

What other medicines interact with Rocuronium?

MediHelp also lists interactions of Rocuronium with, for example, Amikacin, Bacitracin-neomycin-polymyxin, Capreomycin. The full list is on the Rocuronium page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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