Aller au contenu

Interactions médicamenteuses

Amphotericin b liposomal + Lomustine

Gravité: Modérée

Amphotericin b liposomal and Lomustine: moderate interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

Amphotericin B can cause kidney injury and infusion reactions, while lomustine causes myelosuppression and may add to toxicity. The extent of any true interaction is poorly defined.

Ce que signifie cette interaction, en termes simples

Amphotericin b liposomal and Lomustine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Amphotericin b liposomal belongs to Anti Fungals; Lomustine belongs to Oncology.

Niveau de preuve: Low

Pourquoi elle survient

Mechanism not established; possible additive renal and hematologic toxicity.

Conduite à tenir

Monitor renal function, electrolytes and blood counts, and observe for hypotension or bronchospasm during infusions.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Amphotericin b liposomal et Lomustine, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.

Questions fréquentes

Can I take Amphotericin b liposomal with Lomustine?

MediHelp rates the interaction as moderate. Amphotericin b liposomal and Lomustine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Amphotericin B can cause kidney injury and infusion reactions, while lomustine causes myelosuppression and may add to toxicity. The extent of any true interaction is poorly defined.

How serious is the interaction between Amphotericin b liposomal and Lomustine?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor renal function, electrolytes and blood counts, and observe for hypotension or bronchospasm during infusions.

What other medicines interact with Lomustine?

MediHelp also lists interactions of Lomustine with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Lomustine page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter