Interactions médicamenteuses
Amphotericin b liposomal + Ifosfamide
Gravité: Modérée
Amphotericin b liposomal and Ifosfamide: moderate interaction.
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Résumé
Both drugs can injure the kidney, so combined use may increase the risk of renal impairment. Infusion-related reactions such as bronchospasm and hypotension are also described with amphotericin.
Ce que signifie cette interaction, en termes simples
Amphotericin b liposomal and Ifosfamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Amphotericin b liposomal belongs to Anti Fungals; Ifosfamide belongs to Oncology.
Pourquoi elle survient
Additive nephrotoxicity; the mechanism for any other enhanced toxicity is not established.
Conduite à tenir
Monitor serum creatinine, electrolytes (potassium, magnesium) and urine output regularly, and maintain adequate hydration. Consider an alternative antifungal if renal function declines.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Ifosfamide
- Adenovirus types 4 and 7 live + Ifosfamide Contre-indiquée
- Ifosfamide + Measles mumps and rubella vaccine Contre-indiquée
- Ifosfamide + Measles mumps and rubella vaccine live Contre-indiquée
- Ifosfamide + Measles mumps rubella and varicella vaccine live Contre-indiquée
- Ifosfamide + Measles vaccine Contre-indiquée
- Ifosfamide + Rotavirus oral vaccine live Contre-indiquée
Autres interactions de Amphotericin b liposomal
- Amlodipine-benazepril + Amphotericin b liposomal Modérée
- Amphotericin b liposomal + Benazepril Modérée
- Amphotericin b liposomal + Captopril-hydrochlorothiazide Modérée
- Amphotericin b liposomal + Deflazacort Modérée
- Amphotericin b liposomal + Dichlorphenamide Modérée
- Amphotericin b liposomal + Lomustine Modérée
Questions fréquentes
Can I take Amphotericin b liposomal with Ifosfamide?
MediHelp rates the interaction as moderate. Amphotericin b liposomal and Ifosfamide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs can injure the kidney, so combined use may increase the risk of renal impairment. Infusion-related reactions such as bronchospasm and hypotension are also described with amphotericin.
How serious is the interaction between Amphotericin b liposomal and Ifosfamide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum creatinine, electrolytes (potassium, magnesium) and urine output regularly, and maintain adequate hydration. Consider an alternative antifungal if renal function declines.
What other medicines interact with Ifosfamide?
MediHelp also lists interactions of Ifosfamide with, for example, Adenovirus types 4 and 7 live, Measles mumps and rubella vaccine, Measles mumps and rubella vaccine live. The full list is on the Ifosfamide page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.