Interactions médicamenteuses
Atidarsagene autotemcel + Measles mumps and rubella vaccine
Gravité: Majeure
Atidarsagene autotemcel and Measles mumps and rubella vaccine: major interaction.
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Résumé
Atidarsagene autotemcel requires myeloablative conditioning, leaving patients immunosuppressed until hematologic recovery. Live MMR vaccine in this period could cause disseminated vaccine-strain infection and would be ineffective.
Ce que signifie cette interaction, en termes simples
Atidarsagene autotemcel and Measles mumps and rubella vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Atidarsagene autotemcel belongs to Miscellaneous; Measles mumps and rubella vaccine belongs to Miscellaneous.
Pourquoi elle survient
Myeloablative conditioning and hematopoietic reconstitution cause profound immunosuppression, allowing replication of live attenuated virus.
Conduite à tenir
Give MMR at least 6 weeks before conditioning where feasible; defer live vaccines until hematologic and immune recovery is confirmed.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contre-indiquée
- Anakinra + Measles mumps and rubella vaccine Contre-indiquée
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contre-indiquée
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contre-indiquée
- Azathioprine + Measles mumps and rubella vaccine Contre-indiquée
- Basiliximab + Measles mumps and rubella vaccine Contre-indiquée
Autres interactions de Atidarsagene autotemcel
Questions fréquentes
Can I take Atidarsagene autotemcel with Measles mumps and rubella vaccine?
MediHelp rates the interaction as major. Atidarsagene autotemcel and Measles mumps and rubella vaccine can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Atidarsagene autotemcel requires myeloablative conditioning, leaving patients immunosuppressed until hematologic recovery. Live MMR vaccine in this period could cause disseminated vaccine-strain infection and would be ineffective.
How serious is the interaction between Atidarsagene autotemcel and Measles mumps and rubella vaccine?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Give MMR at least 6 weeks before conditioning where feasible; defer live vaccines until hematologic and immune recovery is confirmed.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
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