Interactions médicamenteuses
Atropine + Dicyclomine
Gravité: Modérée
Atropine and Dicyclomine: moderate interaction.
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Résumé
Both drugs are antimuscarinic agents, so their effects add together. Patients may develop dry mouth, blurred vision, urinary retention, constipation, tachycardia, confusion and heat intolerance, particularly the elderly.
Ce que signifie cette interaction, en termes simples
Atropine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Atropine belongs to Miscellaneous; Dicyclomine belongs to Respiratory.
Pourquoi elle survient
Additive blockade of muscarinic acetylcholine receptors.
Conduite à tenir
Avoid routine duplication of antimuscarinic therapy; if both are needed, use the lowest effective doses and monitor for anticholinergic toxicity such as urinary retention, delirium and tachycardia.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Dicyclomine
- Clozapine + Dicyclomine Majeure
- Dicyclomine + Henbane Majeure
- Dicyclomine + Imipramine Majeure
- Dicyclomine + Pramlintide Majeure
- Abobotulinumtoxina + Dicyclomine Modérée
- Aclidinium + Dicyclomine Modérée
Autres interactions de Atropine
- Atropine + Eluxadoline Majeure
- Atropine + Henbane Majeure
- Atropine + Pramlintide Majeure
- Abobotulinumtoxina + Atropine Modérée
- Aclidinium + Atropine Modérée
- Amantadine + Atropine Modérée
Questions fréquentes
Can I take Atropine with Dicyclomine?
MediHelp rates the interaction as moderate. Atropine and Dicyclomine can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs are antimuscarinic agents, so their effects add together. Patients may develop dry mouth, blurred vision, urinary retention, constipation, tachycardia, confusion and heat intolerance, particularly the elderly.
How serious is the interaction between Atropine and Dicyclomine?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid routine duplication of antimuscarinic therapy; if both are needed, use the lowest effective doses and monitor for anticholinergic toxicity such as urinary retention, delirium and tachycardia.
What other medicines interact with Dicyclomine?
MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.
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