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Interactions médicamenteuses

Atropine + Trospium

Gravité: Modérée

Atropine and Trospium: moderate interaction.

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Résumé

Atropine is a systemic antimuscarinic and adds to trospium's effects. This can cause dry mouth, constipation, urinary retention, tachycardia, blurred vision and confusion.

Ce que signifie cette interaction, en termes simples

Atropine and Trospium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Atropine belongs to Miscellaneous; Trospium belongs to Genitourinary.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive antimuscarinic pharmacodynamic effects.

Conduite à tenir

Monitor for anticholinergic toxicity such as urinary retention and tachycardia. Reduce doses or avoid the combination in patients at risk, such as the elderly.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Atropine with Trospium?

MediHelp rates the interaction as moderate. Atropine and Trospium can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Atropine is a systemic antimuscarinic and adds to trospium's effects. This can cause dry mouth, constipation, urinary retention, tachycardia, blurred vision and confusion.

How serious is the interaction between Atropine and Trospium?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for anticholinergic toxicity such as urinary retention and tachycardia. Reduce doses or avoid the combination in patients at risk, such as the elderly.

What other medicines interact with Trospium?

MediHelp also lists interactions of Trospium with, for example, Clozapine, Pramlintide, Thioridazine. The full list is on the Trospium page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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