Interactions médicamenteuses
Bcg vaccine live + Hydrocortisone
Gravité: Majeure
Bcg vaccine live and Hydrocortisone: major interaction.
Dernière mise à jour
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Résumé
Live BCG given to patients on immunosuppressive corticosteroid doses may cause disseminated BCG infection. Corticosteroids also reduce the immune response to the vaccine.
Ce que signifie cette interaction, en termes simples
Bcg vaccine live and Hydrocortisone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Corticosteroid immunosuppression permits uncontrolled replication of live attenuated organisms.
Conduite à tenir
Avoid live BCG in patients on immunosuppressive doses; defer vaccination until steroids are stopped or reduced to low doses, as per product labeling.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Hydrocortisone
- Hydrocortisone + Mifepristone Contre-indiquée
- Hydrocortisone + Poliovirus vaccine live oral trivalent Contre-indiquée
- Hydrocortisone + Smallpox vaccine live Contre-indiquée
- Adenovirus types 4 and 7 live + Hydrocortisone Majeure
- Aldesleukin + Hydrocortisone Majeure
- Aspirin + Hydrocortisone Majeure
Questions fréquentes
Can I take Bcg vaccine live with Hydrocortisone?
MediHelp rates the interaction as major. Bcg vaccine live and Hydrocortisone can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Live BCG given to patients on immunosuppressive corticosteroid doses may cause disseminated BCG infection. Corticosteroids also reduce the immune response to the vaccine.
How serious is the interaction between Bcg vaccine live and Hydrocortisone?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live BCG in patients on immunosuppressive doses; defer vaccination until steroids are stopped or reduced to low doses, as per product labeling.
What other medicines interact with Hydrocortisone?
MediHelp also lists interactions of Hydrocortisone with, for example, Mifepristone, Poliovirus vaccine live oral trivalent, Smallpox vaccine live. The full list is on the Hydrocortisone page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
