Interactions médicamenteuses
Hydrocortisone + Poliovirus vaccine live oral trivalent
Gravité: Contre-indiquée
Hydrocortisone and Poliovirus vaccine live oral trivalent: contraindicated interaction.
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Résumé
Oral polio vaccine is live attenuated and in immunosuppressed patients can cause vaccine-associated paralytic poliomyelitis. Immunosuppressive doses of hydrocortisone also reduce immune response.
Ce que signifie cette interaction, en termes simples
Hydrocortisone and Poliovirus vaccine live oral trivalent are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Corticosteroid-induced immunosuppression permits prolonged replication of live attenuated poliovirus and reduces immunogenicity.
Conduite à tenir
Do not use live oral polio vaccine in patients on immunosuppressive corticosteroids; use inactivated polio vaccine instead. Household contacts should also preferably receive inactivated vaccine.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Hydrocortisone
- Hydrocortisone + Mifepristone Contre-indiquée
- Hydrocortisone + Smallpox vaccine live Contre-indiquée
- Adenovirus types 4 and 7 live + Hydrocortisone Majeure
- Aldesleukin + Hydrocortisone Majeure
- Aspirin + Hydrocortisone Majeure
- Bcg vaccine live + Hydrocortisone Majeure
Questions fréquentes
Can I take Hydrocortisone with Poliovirus vaccine live oral trivalent?
MediHelp rates the interaction as contraindicated. Hydrocortisone and Poliovirus vaccine live oral trivalent are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oral polio vaccine is live attenuated and in immunosuppressed patients can cause vaccine-associated paralytic poliomyelitis. Immunosuppressive doses of hydrocortisone also reduce immune response.
How serious is the interaction between Hydrocortisone and Poliovirus vaccine live oral trivalent?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use live oral polio vaccine in patients on immunosuppressive corticosteroids; use inactivated polio vaccine instead. Household contacts should also preferably receive inactivated vaccine.
What other medicines interact with Hydrocortisone?
MediHelp also lists interactions of Hydrocortisone with, for example, Mifepristone, Smallpox vaccine live, Adenovirus types 4 and 7 live. The full list is on the Hydrocortisone page.
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