Interactions médicamenteuses
Bcg vaccine live + Mycophenolate mofetil
Gravité: Contre-indiquée
Bcg vaccine live and Mycophenolate mofetil: contraindicated interaction.
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Résumé
Live BCG can cause disseminated BCG infection in patients taking mycophenolate, and the vaccine response may be reduced. Live vaccines are contraindicated in significantly immunosuppressed patients.
Ce que signifie cette interaction, en termes simples
Bcg vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Mycophenolate impairs lymphocyte-mediated control of live attenuated mycobacteria and blunts vaccine response.
Conduite à tenir
Do not give BCG vaccine during mycophenolate therapy; consider alternative TB prevention strategies and screening.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contre-indiquée
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contre-indiquée
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contre-indiquée
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contre-indiquée
- Measles vaccine + Mycophenolate mofetil Contre-indiquée
- Mycophenolate mofetil + Rotavirus oral vaccine live Contre-indiquée
Questions fréquentes
Can I take Bcg vaccine live with Mycophenolate mofetil?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live BCG can cause disseminated BCG infection in patients taking mycophenolate, and the vaccine response may be reduced. Live vaccines are contraindicated in significantly immunosuppressed patients.
How serious is the interaction between Bcg vaccine live and Mycophenolate mofetil?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give BCG vaccine during mycophenolate therapy; consider alternative TB prevention strategies and screening.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Influenza virus vaccine quadrivalent intranasal, Measles mumps and rubella vaccine live. The full list is on the Mycophenolate mofetil page.
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