Interactions médicamenteuses
Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil
Gravité: Contre-indiquée
Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil: contraindicated interaction.
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Résumé
This live attenuated combination vaccine can cause disseminated measles or varicella vaccine-strain disease in patients taking mycophenolate. Vaccine response may also be poor.
Ce que signifie cette interaction, en termes simples
Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Mycophenolate-induced lymphocyte suppression permits replication of live attenuated viruses.
Conduite à tenir
Avoid during treatment and vaccinate at least 4 weeks before starting if feasible. Immunise household contacts and use post-exposure prophylaxis if exposed.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contre-indiquée
- Bcg vaccine live + Mycophenolate mofetil Contre-indiquée
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contre-indiquée
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contre-indiquée
- Measles vaccine + Mycophenolate mofetil Contre-indiquée
- Mycophenolate mofetil + Rotavirus oral vaccine live Contre-indiquée
Questions fréquentes
Can I take Measles mumps rubella and varicella vaccine live with Mycophenolate mofetil?
MediHelp rates the interaction as contraindicated. Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live attenuated combination vaccine can cause disseminated measles or varicella vaccine-strain disease in patients taking mycophenolate. Vaccine response may also be poor.
How serious is the interaction between Measles mumps rubella and varicella vaccine live and Mycophenolate mofetil?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid during treatment and vaccinate at least 4 weeks before starting if feasible. Immunise household contacts and use post-exposure prophylaxis if exposed.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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