Interactions médicamenteuses
Measles mumps and rubella vaccine live + Mycophenolate mofetil
Gravité: Contre-indiquée
Measles mumps and rubella vaccine live and Mycophenolate mofetil: contraindicated interaction.
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Résumé
MMR is a live attenuated vaccine and may cause disseminated infection in patients on mycophenolate. Immunosuppression can also reduce vaccine effectiveness.
Ce que signifie cette interaction, en termes simples
Measles mumps and rubella vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Immunosuppression impairs control of live attenuated viral replication.
Conduite à tenir
Do not give while on mycophenolate. Vaccinate at least 4 weeks before starting therapy where possible, and ensure household contacts are immunised.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contre-indiquée
- Bcg vaccine live + Mycophenolate mofetil Contre-indiquée
- Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil Contre-indiquée
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contre-indiquée
- Measles vaccine + Mycophenolate mofetil Contre-indiquée
- Mycophenolate mofetil + Rotavirus oral vaccine live Contre-indiquée
Questions fréquentes
Can I take Measles mumps and rubella vaccine live with Mycophenolate mofetil?
MediHelp rates the interaction as contraindicated. Measles mumps and rubella vaccine live and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. MMR is a live attenuated vaccine and may cause disseminated infection in patients on mycophenolate. Immunosuppression can also reduce vaccine effectiveness.
How serious is the interaction between Measles mumps and rubella vaccine live and Mycophenolate mofetil?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give while on mycophenolate. Vaccinate at least 4 weeks before starting therapy where possible, and ensure household contacts are immunised.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Mycophenolate mofetil page.
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