Interactions médicamenteuses
Influenza virus vaccine quadrivalent intranasal + Mycophenolate mofetil
Gravité: Contre-indiquée
Influenza virus vaccine quadrivalent intranasal and Mycophenolate mofetil: contraindicated interaction.
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Résumé
The intranasal influenza vaccine contains live attenuated virus, which can replicate in patients taking mycophenolate and cause vaccine-strain disease. Its efficacy may also be reduced. It is contraindicated in significantly immunosuppressed patients.
Ce que signifie cette interaction, en termes simples
Influenza virus vaccine quadrivalent intranasal and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Impaired cellular and humoral immunity from mycophenolate permits uncontrolled replication of live attenuated virus.
Conduite à tenir
Do not use the live intranasal vaccine; give an inactivated injectable influenza vaccine instead.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Mycophenolate mofetil
- Adenovirus types 4 and 7 live + Mycophenolate mofetil Contre-indiquée
- Bcg vaccine live + Mycophenolate mofetil Contre-indiquée
- Measles mumps and rubella vaccine live + Mycophenolate mofetil Contre-indiquée
- Measles mumps rubella and varicella vaccine live + Mycophenolate mofetil Contre-indiquée
- Measles vaccine + Mycophenolate mofetil Contre-indiquée
- Mycophenolate mofetil + Rotavirus oral vaccine live Contre-indiquée
Questions fréquentes
Can I take Influenza virus vaccine quadrivalent intranasal with Mycophenolate mofetil?
MediHelp rates the interaction as contraindicated. Influenza virus vaccine quadrivalent intranasal and Mycophenolate mofetil are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which can replicate in patients taking mycophenolate and cause vaccine-strain disease. Its efficacy may also be reduced. It is contraindicated in significantly immunosuppressed patients.
How serious is the interaction between Influenza virus vaccine quadrivalent intranasal and Mycophenolate mofetil?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use the live intranasal vaccine; give an inactivated injectable influenza vaccine instead.
What other medicines interact with Mycophenolate mofetil?
MediHelp also lists interactions of Mycophenolate mofetil with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Measles mumps and rubella vaccine live. The full list is on the Mycophenolate mofetil page.
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