Interactions médicamenteuses
Bcg vaccine live + Procarbazine
Gravité: Contre-indiquée
Bcg vaccine live and Procarbazine: contraindicated interaction.
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Résumé
Procarbazine suppresses immune function and bone marrow. Live BCG given to an immunosuppressed patient carries a risk of disseminated BCG infection, and the protective response is likely to be reduced.
Ce que signifie cette interaction, en termes simples
Bcg vaccine live and Procarbazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Immunosuppression allows unchecked replication of live attenuated mycobacteria and weakens vaccine response.
Conduite à tenir
Do not give live BCG during procarbazine treatment. Delay vaccination until immune function has recovered, generally at least 3 months after chemotherapy ends.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Procarbazine
- Adenovirus types 4 and 7 live + Procarbazine Contre-indiquée
- Amitriptyline + Procarbazine Contre-indiquée
- Amoxapine + Procarbazine Contre-indiquée
- Atomoxetine + Procarbazine Contre-indiquée
- Brimonidine + Procarbazine Contre-indiquée
- Buspirone + Procarbazine Contre-indiquée
Questions fréquentes
Can I take Bcg vaccine live with Procarbazine?
MediHelp rates the interaction as contraindicated. Bcg vaccine live and Procarbazine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Procarbazine suppresses immune function and bone marrow. Live BCG given to an immunosuppressed patient carries a risk of disseminated BCG infection, and the protective response is likely to be reduced.
How serious is the interaction between Bcg vaccine live and Procarbazine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live BCG during procarbazine treatment. Delay vaccination until immune function has recovered, generally at least 3 months after chemotherapy ends.
What other medicines interact with Procarbazine?
MediHelp also lists interactions of Procarbazine with, for example, Adenovirus types 4 and 7 live, Amitriptyline, Amoxapine. The full list is on the Procarbazine page.
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