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Interactions médicamenteuses

Bevacizumab + Daunorubicin

Gravité: Modérée

Bevacizumab and Daunorubicin: moderate interaction.

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Résumé

Daunorubicin is cardiotoxic, and bevacizumab can cause hypertension and, less commonly, heart failure. Combined use may increase cardiac risk, particularly in patients with prior anthracycline exposure.

Ce que signifie cette interaction, en termes simples

Bevacizumab and Daunorubicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Bevacizumab belongs to Oncology; Daunorubicin belongs to Oncology.

Niveau de preuve: Low

Pourquoi elle survient

Additive cardiotoxicity from anthracycline myocardial injury and VEGF inhibition-related hypertension and cardiac stress.

Conduite à tenir

Assess left ventricular function before and during treatment and monitor blood pressure. Treat hypertension promptly and stop therapy if heart failure develops.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Bevacizumab with Daunorubicin?

MediHelp rates the interaction as moderate. Bevacizumab and Daunorubicin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Daunorubicin is cardiotoxic, and bevacizumab can cause hypertension and, less commonly, heart failure. Combined use may increase cardiac risk, particularly in patients with prior anthracycline exposure.

How serious is the interaction between Bevacizumab and Daunorubicin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Assess left ventricular function before and during treatment and monitor blood pressure. Treat hypertension promptly and stop therapy if heart failure develops.

What other medicines interact with Daunorubicin?

MediHelp also lists interactions of Daunorubicin with, for example, Adenovirus types 4 and 7 live, Belatacept, Cyclosporine. The full list is on the Daunorubicin page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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