Interactions médicamenteuses
Canagliflozin + Somatropin
Gravité: Modérée
Canagliflozin and Somatropin: moderate interaction.
Dernière mise à jour
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Résumé
Somatropin can reduce insulin sensitivity and raise blood glucose, which may partly counteract the glucose-lowering effect of canagliflozin. Glycemic control can worsen after growth hormone is started or the dose is increased.
Ce que signifie cette interaction, en termes simples
Canagliflozin and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Canagliflozin belongs to Endocrine; Somatropin belongs to Endocrine.
Pourquoi elle survient
Pharmacodynamic antagonism: growth hormone induces insulin resistance and increases hepatic glucose output and lipolysis.
Conduite à tenir
Monitor blood glucose and HbA1c when starting or adjusting somatropin. Increase the antidiabetic dose if needed.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Somatropin
- Acarbose + Somatropin Modérée
- Albiglutide + Somatropin Modérée
- Alogliptin-metformin + Somatropin Modérée
- Alogliptin-pioglitazone + Somatropin Modérée
- Alogliptin + Somatropin Modérée
- Betamethasone + Somatropin Modérée
Autres interactions de Canagliflozin
Questions fréquentes
Can I take Canagliflozin with Somatropin?
MediHelp rates the interaction as moderate. Canagliflozin and Somatropin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Somatropin can reduce insulin sensitivity and raise blood glucose, which may partly counteract the glucose-lowering effect of canagliflozin. Glycemic control can worsen after growth hormone is started or the dose is increased.
How serious is the interaction between Canagliflozin and Somatropin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor blood glucose and HbA1c when starting or adjusting somatropin. Increase the antidiabetic dose if needed.
What other medicines interact with Somatropin?
MediHelp also lists interactions of Somatropin with, for example, Acarbose, Albiglutide, Alogliptin-metformin. The full list is on the Somatropin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
