Interactions médicamenteuses
Capreomycin + Vancomycin
Gravité: Majeure
Capreomycin and Vancomycin: major interaction.
Dernière mise à jour
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Résumé
Both drugs can damage the kidneys and the inner ear, so combined use may increase the risk of nephrotoxicity and ototoxicity. Capreomycin is itself a significant nephrotoxin and ototoxin, so the combination deserves more than minor concern.
Ce que signifie cette interaction, en termes simples
Capreomycin and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Pourquoi elle survient
Additive nephrotoxic and ototoxic effects of both agents.
Conduite à tenir
Avoid the combination where possible; if unavoidable, monitor serum creatinine, vancomycin trough levels and hearing regularly and adjust doses to renal function.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
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Autres interactions de Vancomycin
- Amikacin + Vancomycin Majeure
- Bacitracin + Vancomycin Majeure
- Cephaloridine + Vancomycin Majeure
- Cidofovir + Vancomycin Majeure
- Cisplatin + Vancomycin Majeure
- Colistin + Vancomycin Majeure
Questions fréquentes
Can I take Capreomycin with Vancomycin?
MediHelp rates the interaction as major. Capreomycin and Vancomycin can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Both drugs can damage the kidneys and the inner ear, so combined use may increase the risk of nephrotoxicity and ototoxicity. Capreomycin is itself a significant nephrotoxin and ototoxin, so the combination deserves more than minor concern.
How serious is the interaction between Capreomycin and Vancomycin?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the combination where possible; if unavoidable, monitor serum creatinine, vancomycin trough levels and hearing regularly and adjust doses to renal function.
What other medicines interact with Vancomycin?
MediHelp also lists interactions of Vancomycin with, for example, Amikacin, Bacitracin, Cephaloridine. The full list is on the Vancomycin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
