Interactions médicamenteuses
Cefixime + Sodium picosulfate / magnesium oxide / anhydrous citric acid
Gravité: Modérée
Cefixime and Sodium picosulfate / magnesium oxide / anhydrous citric acid: moderate interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Sodium picosulfate is a prodrug that must be converted to its active form by colonic bacteria. Antibiotics that suppress gut flora may reduce this conversion and lead to a less effective bowel cleansing before colonoscopy.
Ce que signifie cette interaction, en termes simples
Cefixime and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Pourquoi elle survient
Antibiotic suppression of colonic bacteria reduces conversion of picosulfate to its active laxative metabolite.
Conduite à tenir
If possible, avoid starting the antibiotic until after the bowel preparation has been completed. Assess the quality of bowel cleansing and be prepared to use an additional preparation if it is inadequate.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Cefixime et Sodium picosulfate / magnesium oxide / anhydrous citric acid, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 14 jours sur le web. Sans carte.
Autres interactions de Cefixime
- Cefixime + Typhoid vaccine live Majeure
- Cefixime + Cholera vaccine Modérée
- Cefixime + Kanamycin Modérée
- Cefixime + Microbiota Modérée
- Cefixime + Plazomicin Modérée
- Cefixime + Warfarin Modérée
Questions fréquentes
Can I take Cefixime with Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates the interaction as moderate. Cefixime and Sodium picosulfate / magnesium oxide / anhydrous citric acid can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Sodium picosulfate is a prodrug that must be converted to its active form by colonic bacteria. Antibiotics that suppress gut flora may reduce this conversion and lead to a less effective bowel cleansing before colonoscopy.
How serious is the interaction between Cefixime and Sodium picosulfate / magnesium oxide / anhydrous citric acid?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: If possible, avoid starting the antibiotic until after the bowel preparation has been completed. Assess the quality of bowel cleansing and be prepared to use an additional preparation if it is inadequate.
What other medicines interact with Cefixime?
MediHelp also lists interactions of Cefixime with, for example, Typhoid vaccine live, Cholera vaccine, Kanamycin. The full list is on the Cefixime page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
