Aller au contenu

Interactions médicamenteuses

Chloroprocaine + Timolol

Gravité: Modérée

Chloroprocaine and Timolol: moderate interaction.

Dernière mise à jour

Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.

Le contenu clinique de cette page n'est disponible qu'en anglais.

Résumé

If chloroprocaine is given with epinephrine, nonselective beta-blockade such as timolol can leave alpha-mediated pressor effects unopposed. This can produce hypertension with reflex bradycardia.

Ce que signifie cette interaction, en termes simples

Chloroprocaine and Timolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Chloroprocaine belongs to Central Nervous System; Timolol belongs to Cardiovascular.

Niveau de preuve: Low

Pourquoi elle survient

Timolol blocks beta-2 vasodilation, leaving epinephrine's alpha-mediated vasoconstriction unopposed.

Conduite à tenir

Continue the beta-blocker perioperatively, use the lowest epinephrine dose or an epinephrine-free preparation, and monitor blood pressure and heart rate.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

Réservé aux membres Pro+

Débloquer la page complète

Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Chloroprocaine et Timolol, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.

  • Full clinical management advice
  • Additional notes
  • Evidence detail
  • Interaction checker for a whole prescription

Essayez Pro+ gratuitement pendant 7 jours sur le web. Sans carte.

Questions fréquentes

Can I take Chloroprocaine with Timolol?

MediHelp rates the interaction as moderate. Chloroprocaine and Timolol can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. If chloroprocaine is given with epinephrine, nonselective beta-blockade such as timolol can leave alpha-mediated pressor effects unopposed. This can produce hypertension with reflex bradycardia.

How serious is the interaction between Chloroprocaine and Timolol?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Continue the beta-blocker perioperatively, use the lowest epinephrine dose or an epinephrine-free preparation, and monitor blood pressure and heart rate.

What other medicines interact with Timolol?

MediHelp also lists interactions of Timolol with, for example, Acebutolol, Albuterol, Aldesleukin. The full list is on the Timolol page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

Parcourir de A à Z · Interactions médicamenteuses

Télécharger l'app Se connecter