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Interactions médicamenteuses

Cholecalciferol + Magnesium citrate

Gravité: Modérée

Cholecalciferol and Magnesium citrate: moderate interaction.

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Résumé

Vitamin D enhances intestinal magnesium absorption, and in renal impairment magnesium may accumulate. Hypermagnesemia can cause weakness, hypotension and cardiac conduction problems.

Ce que signifie cette interaction, en termes simples

Cholecalciferol and Magnesium citrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Cholecalciferol belongs to Musculoskeletal; Magnesium citrate belongs to Gastrointestinal Tract.

Niveau de preuve: Low

Pourquoi elle survient

Vitamin D increases gastrointestinal magnesium absorption, while reduced renal excretion permits accumulation.

Conduite à tenir

Avoid regular magnesium-containing products in patients with chronic kidney disease taking vitamin D; monitor serum magnesium if needed.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Cholecalciferol with Magnesium citrate?

MediHelp rates the interaction as moderate. Cholecalciferol and Magnesium citrate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Vitamin D enhances intestinal magnesium absorption, and in renal impairment magnesium may accumulate. Hypermagnesemia can cause weakness, hypotension and cardiac conduction problems.

How serious is the interaction between Cholecalciferol and Magnesium citrate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid regular magnesium-containing products in patients with chronic kidney disease taking vitamin D; monitor serum magnesium if needed.

What other medicines interact with Cholecalciferol?

MediHelp also lists interactions of Cholecalciferol with, for example, Digoxin, Aluminum hydroxide, Calcium acetate. The full list is on the Cholecalciferol page.

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