Interactions médicamenteuses
Cortisone + Mifepristone
Gravité: Contre-indiquée
Cortisone and Mifepristone: contraindicated interaction.
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Résumé
Mifepristone blocks glucocorticoid receptors, so it may reduce the effect of cortisone and precipitate adrenal insufficiency in patients who depend on long-term corticosteroids. Labeling contraindicates mifepristone for abortion in patients on long-term corticosteroid therapy.
Ce que signifie cette interaction, en termes simples
Cortisone and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Mifepristone antagonizes glucocorticoid receptors, opposing the effect of cortisone.
Conduite à tenir
Do not use mifepristone in patients on long-term corticosteroid replacement or treatment. Choose another abortion method or manage under specialist supervision.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Mifepristone
- Apixaban + Mifepristone Contre-indiquée
- Argatroban + Mifepristone Contre-indiquée
- Cisapride + Mifepristone Contre-indiquée
- Cyclosporin + Mifepristone Contre-indiquée
- Dabigatran etexilate + Mifepristone Contre-indiquée
- Dalteparin + Mifepristone Contre-indiquée
Questions fréquentes
Can I take Cortisone with Mifepristone?
MediHelp rates the interaction as contraindicated. Cortisone and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mifepristone blocks glucocorticoid receptors, so it may reduce the effect of cortisone and precipitate adrenal insufficiency in patients who depend on long-term corticosteroids. Labeling contraindicates mifepristone for abortion in patients on long-term corticosteroid therapy.
How serious is the interaction between Cortisone and Mifepristone?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not use mifepristone in patients on long-term corticosteroid replacement or treatment. Choose another abortion method or manage under specialist supervision.
What other medicines interact with Mifepristone?
MediHelp also lists interactions of Mifepristone with, for example, Apixaban, Argatroban, Cisapride. The full list is on the Mifepristone page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
