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Interactions médicamenteuses

Dalteparin + Mifepristone

Gravité: Contre-indiquée

Dalteparin and Mifepristone: contraindicated interaction.

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Résumé

Mifepristone is used for medical termination of pregnancy and can cause prolonged or heavy uterine bleeding. In a patient receiving dalteparin, the impaired haemostasis can turn this into excessive or hazardous haemorrhage.

Ce que signifie cette interaction, en termes simples

Dalteparin and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.

Dalteparin belongs to Cardiovascular; Mifepristone belongs to Endocrine.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive haemorrhagic risk (uterine bleeding plus anticoagulation)

Conduite à tenir

Mifepristone labelling contraindicates concurrent anticoagulant therapy; use an alternative approach or manage anticoagulation specialist-led before any termination.

Questions à poser à votre pharmacien

  • Is there an alternative to one of these two medicines for me?
  • If both are essential, who is monitoring me and how often?
  • Which symptoms mean I should stop and seek help straight away?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Dalteparin with Mifepristone?

MediHelp rates the interaction as contraindicated. Dalteparin and Mifepristone are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Mifepristone is used for medical termination of pregnancy and can cause prolonged or heavy uterine bleeding. In a patient receiving dalteparin, the impaired haemostasis can turn this into excessive or hazardous haemorrhage.

How serious is the interaction between Dalteparin and Mifepristone?

MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Mifepristone labelling contraindicates concurrent anticoagulant therapy; use an alternative approach or manage anticoagulation specialist-led before any termination.

What other medicines interact with Dalteparin?

MediHelp also lists interactions of Dalteparin with, for example, Defibrotide, Ketorolac, Abciximab. The full list is on the Dalteparin page.

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