Interactions médicamenteuses
Dapagliflozin + Glipizide-metformin
Gravité: Modérée
Dapagliflozin and Glipizide-metformin: moderate interaction.
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Résumé
Dapagliflozin adds glucose-lowering effect to glipizide, increasing the risk of hypoglycemia. The risk is mainly related to the sulfonylurea component.
Ce que signifie cette interaction, en termes simples
Dapagliflozin and Glipizide-metformin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Dapagliflozin belongs to Endocrine; Glipizide-metformin belongs to Endocrine.
Pourquoi elle survient
Additive glucose lowering, with SGLT2 inhibition added to sulfonylurea-driven insulin secretion.
Conduite à tenir
Consider reducing the glipizide dose when dapagliflozin is started and monitor blood glucose closely.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Glipizide-metformin
Autres interactions de Dapagliflozin
- Chlorpropamide + Dapagliflozin Modérée
- Dapagliflozin + Glibenclamide Modérée
- Dapagliflozin + Gliclazide Modérée
- Dapagliflozin + Glimepiride Modérée
- Dapagliflozin + Glimepiride-pioglitazone Modérée
- Dapagliflozin + Glipizide Modérée
Questions fréquentes
Can I take Dapagliflozin with Glipizide-metformin?
MediHelp rates the interaction as moderate. Dapagliflozin and Glipizide-metformin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Dapagliflozin adds glucose-lowering effect to glipizide, increasing the risk of hypoglycemia. The risk is mainly related to the sulfonylurea component.
How serious is the interaction between Dapagliflozin and Glipizide-metformin?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider reducing the glipizide dose when dapagliflozin is started and monitor blood glucose closely.
What other medicines interact with Glipizide-metformin?
MediHelp also lists interactions of Glipizide-metformin with, for example, Contrast media, Diatrizoate meglumine / diatrizoate, Diatrizoate. The full list is on the Glipizide-metformin page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
