Interactions médicamenteuses
Deflazacort + Influenza virus vaccine quadrivalent intranasal
Gravité: Contre-indiquée
Deflazacort and Influenza virus vaccine quadrivalent intranasal: contraindicated interaction.
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Résumé
The intranasal influenza vaccine contains live attenuated virus, which may replicate more than intended in a patient immunosuppressed by deflazacort. Vaccine efficacy may also be reduced.
Ce que signifie cette interaction, en termes simples
Deflazacort and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Glucocorticoid immunosuppression impairs clearance of live attenuated virus and the vaccine immune response.
Conduite à tenir
Avoid the live intranasal vaccine in patients on immunosuppressive doses of deflazacort and use the inactivated injectable vaccine instead.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contre-indiquée
- Bcg vaccine live + Deflazacort Contre-indiquée
- Deflazacort + Measles mumps and rubella vaccine Contre-indiquée
- Deflazacort + Measles mumps and rubella vaccine live Contre-indiquée
- Deflazacort + Measles mumps rubella and varicella vaccine live Contre-indiquée
- Deflazacort + Measles vaccine Contre-indiquée
Questions fréquentes
Can I take Deflazacort with Influenza virus vaccine quadrivalent intranasal?
MediHelp rates the interaction as contraindicated. Deflazacort and Influenza virus vaccine quadrivalent intranasal are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. The intranasal influenza vaccine contains live attenuated virus, which may replicate more than intended in a patient immunosuppressed by deflazacort. Vaccine efficacy may also be reduced.
How serious is the interaction between Deflazacort and Influenza virus vaccine quadrivalent intranasal?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid the live intranasal vaccine in patients on immunosuppressive doses of deflazacort and use the inactivated injectable vaccine instead.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Measles mumps and rubella vaccine. The full list is on the Deflazacort page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
