Interactions médicamenteuses
Deflazacort + Measles mumps and rubella vaccine
Gravité: Contre-indiquée
Deflazacort and Measles mumps and rubella vaccine: contraindicated interaction.
Dernière mise à jour
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Résumé
Deflazacort given chronically is immunosuppressive, and live attenuated vaccines such as measles, mumps, rubella and varicella can replicate unchecked in an immunosuppressed host. This can cause vaccine-strain disease, and the immune response to the vaccine is also reduced.
Ce que signifie cette interaction, en termes simples
Deflazacort and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Deflazacort belongs to Miscellaneous; Measles mumps and rubella vaccine belongs to Miscellaneous.
Pourquoi elle survient
Corticosteroid immunosuppression permits live-vaccine replication and impairs response
Conduite à tenir
Avoid live vaccines during deflazacort therapy at immunosuppressive doses and for at least 4 weeks (ideally per specialist guidance) after stopping; complete live vaccinations at least 4 weeks before starting if possible.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Measles mumps and rubella vaccine
- Adalimumab + Measles mumps and rubella vaccine Contre-indiquée
- Anakinra + Measles mumps and rubella vaccine Contre-indiquée
- Antithymocyte globulin equine + Measles mumps and rubella vaccine Contre-indiquée
- Antithymocyte globulin rabbit + Measles mumps and rubella vaccine Contre-indiquée
- Azathioprine + Measles mumps and rubella vaccine Contre-indiquée
- Basiliximab + Measles mumps and rubella vaccine Contre-indiquée
Autres interactions de Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contre-indiquée
- Bcg vaccine live + Deflazacort Contre-indiquée
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Deflazacort + Measles mumps and rubella vaccine live Contre-indiquée
- Deflazacort + Measles mumps rubella and varicella vaccine live Contre-indiquée
- Deflazacort + Measles vaccine Contre-indiquée
Questions fréquentes
Can I take Deflazacort with Measles mumps and rubella vaccine?
MediHelp rates the interaction as contraindicated. Deflazacort and Measles mumps and rubella vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Deflazacort given chronically is immunosuppressive, and live attenuated vaccines such as measles, mumps, rubella and varicella can replicate unchecked in an immunosuppressed host. This can cause vaccine-strain disease, and the immune response to the vaccine is also reduced.
How serious is the interaction between Deflazacort and Measles mumps and rubella vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid live vaccines during deflazacort therapy at immunosuppressive doses and for at least 4 weeks (ideally per specialist guidance) after stopping; complete live vaccinations at least 4 weeks before starting if possible.
What other medicines interact with Measles mumps and rubella vaccine?
MediHelp also lists interactions of Measles mumps and rubella vaccine with, for example, Adalimumab, Anakinra, Antithymocyte globulin equine. The full list is on the Measles mumps and rubella vaccine page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
