Interactions médicamenteuses
Deflazacort + Measles vaccine
Gravité: Contre-indiquée
Deflazacort and Measles vaccine: contraindicated interaction.
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Résumé
Measles vaccine contains live attenuated virus that may cause disseminated disease in a patient immunosuppressed by deflazacort. The vaccine response may also be inadequate.
Ce que signifie cette interaction, en termes simples
Deflazacort and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Glucocorticoid immunosuppression impairs control of live attenuated virus replication and blunts immunity.
Conduite à tenir
Do not give at immunosuppressive doses; vaccinate at least the labeled interval after stopping steroids, or before starting them. For exposure, consider immunoglobulin rather than vaccine.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contre-indiquée
- Bcg vaccine live + Deflazacort Contre-indiquée
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Deflazacort + Measles mumps and rubella vaccine Contre-indiquée
- Deflazacort + Measles mumps and rubella vaccine live Contre-indiquée
- Deflazacort + Measles mumps rubella and varicella vaccine live Contre-indiquée
Questions fréquentes
Can I take Deflazacort with Measles vaccine?
MediHelp rates the interaction as contraindicated. Deflazacort and Measles vaccine are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Measles vaccine contains live attenuated virus that may cause disseminated disease in a patient immunosuppressed by deflazacort. The vaccine response may also be inadequate.
How serious is the interaction between Deflazacort and Measles vaccine?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give at immunosuppressive doses; vaccinate at least the labeled interval after stopping steroids, or before starting them. For exposure, consider immunoglobulin rather than vaccine.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
