Interactions médicamenteuses
Deflazacort + Measles mumps rubella and varicella vaccine live
Gravité: Contre-indiquée
Deflazacort and Measles mumps rubella and varicella vaccine live: contraindicated interaction.
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Résumé
This live vaccine includes varicella virus along with MMR, and replication may be uncontrolled in patients immunosuppressed by deflazacort. This can cause disseminated vaccine-strain disease and a poor immune response.
Ce que signifie cette interaction, en termes simples
Deflazacort and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Glucocorticoid immunosuppression impairs control of live attenuated viruses and reduces vaccine immunogenicity.
Conduite à tenir
Do not administer during immunosuppressive steroid therapy; schedule before starting steroids or after the labeled washout. Use post-exposure measures instead if exposed.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Deflazacort
- Adenovirus types 4 and 7 live + Deflazacort Contre-indiquée
- Bcg vaccine live + Deflazacort Contre-indiquée
- Deflazacort + Influenza virus vaccine quadrivalent intranasal Contre-indiquée
- Deflazacort + Measles mumps and rubella vaccine Contre-indiquée
- Deflazacort + Measles mumps and rubella vaccine live Contre-indiquée
- Deflazacort + Measles vaccine Contre-indiquée
Questions fréquentes
Can I take Deflazacort with Measles mumps rubella and varicella vaccine live?
MediHelp rates the interaction as contraindicated. Deflazacort and Measles mumps rubella and varicella vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. This live vaccine includes varicella virus along with MMR, and replication may be uncontrolled in patients immunosuppressed by deflazacort. This can cause disseminated vaccine-strain disease and a poor immune response.
How serious is the interaction between Deflazacort and Measles mumps rubella and varicella vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not administer during immunosuppressive steroid therapy; schedule before starting steroids or after the labeled washout. Use post-exposure measures instead if exposed.
What other medicines interact with Deflazacort?
MediHelp also lists interactions of Deflazacort with, for example, Adenovirus types 4 and 7 live, Bcg vaccine live, Influenza virus vaccine quadrivalent intranasal. The full list is on the Deflazacort page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
