Interactions médicamenteuses
Dexamethasone + Smallpox vaccine live
Gravité: Contre-indiquée
Dexamethasone and Smallpox vaccine live: contraindicated interaction.
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Résumé
Live vaccinia vaccine in a patient on immunosuppressive corticosteroids risks progressive vaccinia and other serious complications, along with reduced vaccine response.
Ce que signifie cette interaction, en termes simples
Dexamethasone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Glucocorticoid immunosuppression permits uncontrolled replication of live vaccinia virus.
Conduite à tenir
Avoid in patients on immunosuppressive steroid doses outside of a high-risk exposure scenario where specialist advice weighs the risk. Otherwise delay until steroids are stopped and immune function recovers.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Dexamethasone
- Bcg vaccine live + Dexamethasone Contre-indiquée
- Dexamethasone + Mifepristone Contre-indiquée
- Dexamethasone + Rilpivirine Contre-indiquée
- Dexamethasone + Varicella virus vaccine live Contre-indiquée
- Dexamethasone + Yellow fever vaccine Contre-indiquée
- Dexamethasone + Zoster vaccine live Contre-indiquée
Questions fréquentes
Can I take Dexamethasone with Smallpox vaccine live?
MediHelp rates the interaction as contraindicated. Dexamethasone and Smallpox vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live vaccinia vaccine in a patient on immunosuppressive corticosteroids risks progressive vaccinia and other serious complications, along with reduced vaccine response.
How serious is the interaction between Dexamethasone and Smallpox vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid in patients on immunosuppressive steroid doses outside of a high-risk exposure scenario where specialist advice weighs the risk. Otherwise delay until steroids are stopped and immune function recovers.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
