Interactions médicamenteuses
Dexamethasone + Zoster vaccine live
Gravité: Contre-indiquée
Dexamethasone and Zoster vaccine live: contraindicated interaction.
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Résumé
Live zoster vaccine contains replicating varicella-zoster virus, which may cause disseminated disease in patients on immunosuppressive doses of dexamethasone. The immune response to the vaccine may also be reduced.
Ce que signifie cette interaction, en termes simples
Dexamethasone and Zoster vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Glucocorticoid-induced suppression of cell-mediated immunity allows replication of the attenuated virus.
Conduite à tenir
Do not give live zoster vaccine during high-dose corticosteroid therapy; wait at least 1 month after stopping. Use the recombinant non-live zoster vaccine where available.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Dexamethasone
- Bcg vaccine live + Dexamethasone Contre-indiquée
- Dexamethasone + Mifepristone Contre-indiquée
- Dexamethasone + Rilpivirine Contre-indiquée
- Dexamethasone + Smallpox vaccine live Contre-indiquée
- Dexamethasone + Varicella virus vaccine live Contre-indiquée
- Dexamethasone + Yellow fever vaccine Contre-indiquée
Questions fréquentes
Can I take Dexamethasone with Zoster vaccine live?
MediHelp rates the interaction as contraindicated. Dexamethasone and Zoster vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live zoster vaccine contains replicating varicella-zoster virus, which may cause disseminated disease in patients on immunosuppressive doses of dexamethasone. The immune response to the vaccine may also be reduced.
How serious is the interaction between Dexamethasone and Zoster vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live zoster vaccine during high-dose corticosteroid therapy; wait at least 1 month after stopping. Use the recombinant non-live zoster vaccine where available.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
