Interactions médicamenteuses
Dexamethasone + Varicella virus vaccine live
Gravité: Contre-indiquée
Dexamethasone and Varicella virus vaccine live: contraindicated interaction.
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Résumé
Live varicella vaccine can cause disseminated vaccine-strain varicella in patients who are immunosuppressed by high-dose dexamethasone. The vaccine response may also be reduced.
Ce que signifie cette interaction, en termes simples
Dexamethasone and Varicella virus vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Pourquoi elle survient
Glucocorticoid-induced suppression of cellular immunity permits uncontrolled replication of the attenuated virus.
Conduite à tenir
Do not give live varicella vaccine to patients on immunosuppressive doses of corticosteroids. Wait at least 1 month after stopping high-dose therapy, and vaccinate before starting treatment when possible.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Dexamethasone
- Bcg vaccine live + Dexamethasone Contre-indiquée
- Dexamethasone + Mifepristone Contre-indiquée
- Dexamethasone + Rilpivirine Contre-indiquée
- Dexamethasone + Smallpox vaccine live Contre-indiquée
- Dexamethasone + Yellow fever vaccine Contre-indiquée
- Dexamethasone + Zoster vaccine live Contre-indiquée
Questions fréquentes
Can I take Dexamethasone with Varicella virus vaccine live?
MediHelp rates the interaction as contraindicated. Dexamethasone and Varicella virus vaccine live are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Live varicella vaccine can cause disseminated vaccine-strain varicella in patients who are immunosuppressed by high-dose dexamethasone. The vaccine response may also be reduced.
How serious is the interaction between Dexamethasone and Varicella virus vaccine live?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Do not give live varicella vaccine to patients on immunosuppressive doses of corticosteroids. Wait at least 1 month after stopping high-dose therapy, and vaccinate before starting treatment when possible.
What other medicines interact with Dexamethasone?
MediHelp also lists interactions of Dexamethasone with, for example, Bcg vaccine live, Mifepristone, Rilpivirine. The full list is on the Dexamethasone page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
