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Interactions médicamenteuses

Dicyclomine + Revefenacin

Gravité: Modérée

Dicyclomine and Revefenacin: moderate interaction.

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Résumé

Revefenacin is an inhaled long-acting muscarinic antagonist with low systemic exposure. Combined with oral dicyclomine, additive anticholinergic effects may occur, such as dry mouth, urinary retention and constipation.

Ce que signifie cette interaction, en termes simples

Dicyclomine and Revefenacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Dicyclomine belongs to Respiratory; Revefenacin belongs to Respiratory.

Niveau de preuve: Low

Pourquoi elle survient

Additive antimuscarinic effects at peripheral cholinergic receptors.

Conduite à tenir

Monitor for urinary retention, constipation, dry mouth and narrow-angle glaucoma symptoms. Reduce or stop dicyclomine if anticholinergic effects develop.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Dicyclomine with Revefenacin?

MediHelp rates the interaction as moderate. Dicyclomine and Revefenacin can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Revefenacin is an inhaled long-acting muscarinic antagonist with low systemic exposure. Combined with oral dicyclomine, additive anticholinergic effects may occur, such as dry mouth, urinary retention and constipation.

How serious is the interaction between Dicyclomine and Revefenacin?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor for urinary retention, constipation, dry mouth and narrow-angle glaucoma symptoms. Reduce or stop dicyclomine if anticholinergic effects develop.

What other medicines interact with Dicyclomine?

MediHelp also lists interactions of Dicyclomine with, for example, Clozapine, Henbane, Imipramine. The full list is on the Dicyclomine page.

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