Interactions médicamenteuses
Digoxin + Teriparatide
Gravité: Modérée
Digoxin and Teriparatide: moderate interaction.
Dernière mise à jour
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Résumé
Teriparatide can cause transient rises in serum calcium after dosing. Hypercalcemia increases myocardial sensitivity to digoxin, so toxicity could theoretically occur, although reports are rare.
Ce que signifie cette interaction, en termes simples
Digoxin and Teriparatide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.
Digoxin belongs to Cardiovascular; Teriparatide belongs to Musculoskeletal.
Pourquoi elle survient
Transient teriparatide-induced hypercalcemia sensitizes the myocardium to digitalis glycosides, increasing arrhythmia risk.
Conduite à tenir
Monitor serum calcium and digoxin levels, and watch for signs of digoxin toxicity such as nausea, visual changes and arrhythmias. Adjust the digoxin dose if toxicity is suspected.
Questions à poser à votre pharmacien
- Should I take them at different times of day?
- Does the dose of either medicine need to change?
- Is there anything I should avoid, such as alcohol or certain foods, while on both?
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Autres interactions de Teriparatide
- Alendronate + Teriparatide Mineure
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Questions fréquentes
Can I take Digoxin with Teriparatide?
MediHelp rates the interaction as moderate. Digoxin and Teriparatide can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Teriparatide can cause transient rises in serum calcium after dosing. Hypercalcemia increases myocardial sensitivity to digoxin, so toxicity could theoretically occur, although reports are rare.
How serious is the interaction between Digoxin and Teriparatide?
MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Monitor serum calcium and digoxin levels, and watch for signs of digoxin toxicity such as nausea, visual changes and arrhythmias. Adjust the digoxin dose if toxicity is suspected.
What other medicines interact with Teriparatide?
MediHelp also lists interactions of Teriparatide with, for example, Alendronate, Calcium acetate, Calcium carbonate. The full list is on the Teriparatide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
