Interactions médicamenteuses
Ethinyl estradiol-levonorgestrel + Tranexamic acid
Gravité: Contre-indiquée
Ethinyl estradiol-levonorgestrel and Tranexamic acid: contraindicated interaction.
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Résumé
Combined hormonal contraceptives raise the risk of venous thromboembolism and tranexamic acid is antifibrinolytic, so together the thrombotic risk is increased. Oral tranexamic acid labeling contraindicates its use with combined hormonal contraception.
Ce que signifie cette interaction, en termes simples
Ethinyl estradiol-levonorgestrel and Tranexamic acid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Ethinyl estradiol-levonorgestrel belongs to Endocrine; Tranexamic acid belongs to Cardiovascular.
Pourquoi elle survient
Additive prothrombotic effects from estrogen-induced coagulation changes and antifibrinolysis.
Conduite à tenir
Avoid coadministration; for heavy menstrual bleeding consider a non-hormonal or progestin-only alternative, or an alternative to tranexamic acid.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Ethinyl estradiol-levonorgestrel
- Ethinyl estradiol-levonorgestrel + Fezolinetant Contre-indiquée
- Ethinyl estradiol-levonorgestrel + Ombitasvir / paritaprevir / ritonavir and dasabuvir Contre-indiquée
- Aminocaproic acid + Ethinyl estradiol-levonorgestrel Majeure
- Amobarbital + Ethinyl estradiol-levonorgestrel Majeure
- Anastrozole + Ethinyl estradiol-levonorgestrel Majeure
- Antithrombin alfa + Ethinyl estradiol-levonorgestrel Majeure
Autres interactions de Tranexamic acid
- Dienogest / estradiol valerate + Tranexamic acid Contre-indiquée
- Ethinyl estradiol-drospirenone + Tranexamic acid Contre-indiquée
- Ethinyl estradiol-norgestimate + Tranexamic acid Contre-indiquée
- Ethinylestradiol + Tranexamic acid Contre-indiquée
- Mestranol + Tranexamic acid Contre-indiquée
- Alteplase + Tranexamic acid Majeure
Questions fréquentes
Can I take Ethinyl estradiol-levonorgestrel with Tranexamic acid?
MediHelp rates the interaction as contraindicated. Ethinyl estradiol-levonorgestrel and Tranexamic acid are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Combined hormonal contraceptives raise the risk of venous thromboembolism and tranexamic acid is antifibrinolytic, so together the thrombotic risk is increased. Oral tranexamic acid labeling contraindicates its use with combined hormonal contraception.
How serious is the interaction between Ethinyl estradiol-levonorgestrel and Tranexamic acid?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid coadministration; for heavy menstrual bleeding consider a non-hormonal or progestin-only alternative, or an alternative to tranexamic acid.
What other medicines interact with Ethinyl estradiol-levonorgestrel?
MediHelp also lists interactions of Ethinyl estradiol-levonorgestrel with, for example, Fezolinetant, Ombitasvir / paritaprevir / ritonavir and dasabuvir, Aminocaproic acid. The full list is on the Ethinyl estradiol-levonorgestrel page.
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Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
