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Interactions médicamenteuses

Foscarnet + Pamidronate

Gravité: Modérée

Foscarnet and Pamidronate: moderate interaction.

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Résumé

Both drugs lower serum calcium: pamidronate by inhibiting bone resorption and foscarnet by chelating ionized calcium. Together they may cause symptomatic hypocalcemia with tetany, paresthesias or seizures.

Ce que signifie cette interaction, en termes simples

Foscarnet and Pamidronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken.

Foscarnet belongs to Anti Virals; Pamidronate belongs to Musculoskeletal.

Niveau de preuve: Moderate

Pourquoi elle survient

Additive lowering of serum calcium through bone resorption inhibition and chelation of ionized calcium.

Conduite à tenir

Check calcium, magnesium and ionized calcium before and during therapy, and correct deficits promptly.

Questions à poser à votre pharmacien

  • Should I take them at different times of day?
  • Does the dose of either medicine need to change?
  • Is there anything I should avoid, such as alcohol or certain foods, while on both?

Bring a full list of your medicines, including over-the-counter products, supplements and herbal remedies, to every pharmacy visit.

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Questions fréquentes

Can I take Foscarnet with Pamidronate?

MediHelp rates the interaction as moderate. Foscarnet and Pamidronate can affect each other. The combination is often manageable, but it may need a change of dose, a change of timing, or extra checks while both are taken. Both drugs lower serum calcium: pamidronate by inhibiting bone resorption and foscarnet by chelating ionized calcium. Together they may cause symptomatic hypocalcemia with tetany, paresthesias or seizures.

How serious is the interaction between Foscarnet and Pamidronate?

MediHelp rates it moderate, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check calcium, magnesium and ionized calcium before and during therapy, and correct deficits promptly.

What other medicines interact with Pamidronate?

MediHelp also lists interactions of Pamidronate with, for example, Aluminum hydroxide, Dichlorphenamide, Tenofovir df. The full list is on the Pamidronate page.

Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp

Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.

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