Interactions médicamenteuses
Glipizide + Insulin degludec-liraglutide
Gravité: Majeure
Glipizide and Insulin degludec-liraglutide: major interaction.
Dernière mise à jour
Réservé aux professionnels de santé — à titre de référence uniquement. Cette page est un bref résumé, pas un avis médical, et ne remplace ni la notice officielle ni le jugement clinique. Vérifiez toujours avant de prescrire ou de délivrer.
Le contenu clinique de cette page n'est disponible qu'en anglais.
Résumé
Adding insulin and a GLP-1 agonist to glipizide raises the risk of hypoglycemia, which can be serious. Sulfonylurea doses often need reduction.
Ce que signifie cette interaction, en termes simples
Glipizide and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for.
Glipizide belongs to Endocrine; Insulin degludec-liraglutide belongs to Endocrine.
Pourquoi elle survient
Additive stimulation of insulin secretion and insulin effect, producing synergistic glucose lowering.
Conduite à tenir
Consider lowering the glipizide dose when this combination is started. Monitor glucose frequently and teach the patient to recognize hypoglycemia.
Questions à poser à votre pharmacien
- Does the benefit of taking both outweigh the risk in my case?
- Do I need any blood test, ECG or other check while on both?
- What early warning signs should I watch for, and what should I do if they appear?
Réservé aux membres Pro+
Débloquer la page complète
Créez un compte et lancez un essai Pro+ pour débloquer les conseils complets de prise en charge pour Glipizide et Insulin degludec-liraglutide, les notes complémentaires, le détail des données probantes et le vérificateur d'interactions pour une ordonnance complète.
- Full clinical management advice
- Additional notes
- Evidence detail
- Interaction checker for a whole prescription
Essayez Pro+ gratuitement pendant 14 jours sur le web. Sans carte.
Autres interactions de Insulin degludec-liraglutide
Autres interactions de Glipizide
- Disopyramide + Glipizide Majeure
- Fluconazole + Glipizide Majeure
- Glipizide + Insulin glargine-lixisenatide Majeure
- Glipizide + Sulfamethoxazole Majeure
- Aceclofenac + Glipizide Modérée
- Acemetacin + Glipizide Modérée
Questions fréquentes
Can I take Glipizide with Insulin degludec-liraglutide?
MediHelp rates the interaction as major. Glipizide and Insulin degludec-liraglutide can interact in a way that may be serious. Using them together is sometimes necessary, but it needs a deliberate decision by the prescriber, a plan for monitoring, and clear advice on the warning signs to watch for. Adding insulin and a GLP-1 agonist to glipizide raises the risk of hypoglycemia, which can be serious. Sulfonylurea doses often need reduction.
How serious is the interaction between Glipizide and Insulin degludec-liraglutide?
MediHelp rates it major, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Consider lowering the glipizide dose when this combination is started. Monitor glucose frequently and teach the patient to recognize hypoglycemia.
What other medicines interact with Insulin degludec-liraglutide?
MediHelp also lists interactions of Insulin degludec-liraglutide with, for example, Albiglutide, Chlorpropamide, Clozapine. The full list is on the Insulin degludec-liraglutide page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
