Interactions médicamenteuses
Heparin + Oritavancin
Gravité: Contre-indiquée
Heparin and Oritavancin: contraindicated interaction.
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Résumé
Oritavancin artificially prolongs aPTT for many days, so unfractionated heparin monitoring becomes unreliable. This may lead to inappropriate dosing and bleeding or thrombosis.
Ce que signifie cette interaction, en termes simples
Heparin and Oritavancin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two.
Heparin belongs to Cardiovascular; Oritavancin belongs to Anti Bacterial.
Pourquoi elle survient
Oritavancin binds phospholipid reagents used in coagulation assays, causing laboratory interference rather than a true pharmacodynamic effect.
Conduite à tenir
Avoid IV unfractionated heparin for the period stated in labeling after oritavancin. Use an alternative anticoagulant monitored by a non-aPTT method if needed.
Questions à poser à votre pharmacien
- Is there an alternative to one of these two medicines for me?
- If both are essential, who is monitoring me and how often?
- Which symptoms mean I should stop and seek help straight away?
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Autres interactions de Oritavancin
- Oritavancin + Warfarin Modérée
- Carbamazepine + Oritavancin Mineure
- Cyclosporin + Oritavancin Mineure
- Ethosuximide + Oritavancin Mineure
- Flecainide + Oritavancin Mineure
- Oritavancin + Phenytoin Mineure
Autres interactions de Heparin
- Defibrotide + Heparin Contre-indiquée
- Heparin + Ketorolac Contre-indiquée
- Acemetacin + Heparin Majeure
- Acetylsalicylic acid + Heparin Majeure
- Alteplase + Heparin Majeure
- Andexanet alfa + Heparin Majeure
Questions fréquentes
Can I take Heparin with Oritavancin?
MediHelp rates the interaction as contraindicated. Heparin and Oritavancin are not normally used together. Taking them at the same time is expected to cause harm or make one of them unsafe, so a different medicine is usually chosen for one of the two. Oritavancin artificially prolongs aPTT for many days, so unfractionated heparin monitoring becomes unreliable. This may lead to inappropriate dosing and bleeding or thrombosis.
How serious is the interaction between Heparin and Oritavancin?
MediHelp rates it contraindicated, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Avoid IV unfractionated heparin for the period stated in labeling after oritavancin. Use an alternative anticoagulant monitored by a non-aPTT method if needed.
What other medicines interact with Oritavancin?
MediHelp also lists interactions of Oritavancin with, for example, Warfarin, Carbamazepine, Cyclosporin. The full list is on the Oritavancin page.
Monographies complètes, posologies et vérificateur d'interactions dans l'application MediHelp
Ouvrez le référentiel complet, vérifiez les interactions entre plusieurs médicaments et utilisez les outils de posologie dans l'application MediHelp.
