Interactions médicamenteuses
Cyclosporin + Oritavancin
Gravité: Mineure
Cyclosporin and Oritavancin: minor interaction.
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Résumé
Oritavancin is a weak CYP3A4 inducer and could slightly lower cyclosporine concentrations. Clinical significance is uncertain, but cyclosporine has a narrow therapeutic index so loss of immunosuppression is a theoretical concern.
Ce que signifie cette interaction, en termes simples
Cyclosporin and Oritavancin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised.
Cyclosporin belongs to Miscellaneous; Oritavancin belongs to Anti Bacterial.
Pourquoi elle survient
Weak induction of CYP3A4 by oritavancin may modestly increase cyclosporine metabolism.
Conduite à tenir
Check cyclosporine trough concentrations during and shortly after oritavancin treatment. Adjust the dose only if levels fall below target.
Questions à poser à votre pharmacien
- Is there anything I should notice while taking both?
- Do I need to tell my doctor at the next visit?
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Autres interactions de Cyclosporin
- Adenovirus types 4 and 7 live + Cyclosporin Contre-indiquée
- Aliskiren + Cyclosporin Contre-indiquée
- Bcg vaccine live + Cyclosporin Contre-indiquée
- Bosentan + Cyclosporin Contre-indiquée
- Cidofovir + Cyclosporin Contre-indiquée
- Cyclosporin + Dengue vaccine Contre-indiquée
Autres interactions de Oritavancin
- Heparin + Oritavancin Contre-indiquée
- Oritavancin + Warfarin Modérée
- Carbamazepine + Oritavancin Mineure
- Ethosuximide + Oritavancin Mineure
- Flecainide + Oritavancin Mineure
- Oritavancin + Phenytoin Mineure
Questions fréquentes
Can I take Cyclosporin with Oritavancin?
MediHelp rates the interaction as minor. Cyclosporin and Oritavancin have a small, usually unimportant interaction. Most people can take both; the pharmacist may still mention it so that any unexpected effect is recognised. Oritavancin is a weak CYP3A4 inducer and could slightly lower cyclosporine concentrations. Clinical significance is uncertain, but cyclosporine has a narrow therapeutic index so loss of immunosuppression is a theoretical concern.
How serious is the interaction between Cyclosporin and Oritavancin?
MediHelp rates it minor, on a four-level scale (minor, moderate, major, contraindicated) based on published labels and references. What to do, in brief: Check cyclosporine trough concentrations during and shortly after oritavancin treatment. Adjust the dose only if levels fall below target.
What other medicines interact with Cyclosporin?
MediHelp also lists interactions of Cyclosporin with, for example, Adenovirus types 4 and 7 live, Aliskiren, Bcg vaccine live. The full list is on the Cyclosporin page.
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